IntroductionOncologyRare & OrphanRespiratoryAnti-Infectives & VaccinesDermatology

Therapeutic Focus

Our clinical therapeutic core focus is on Oncology, Rare & Orphan diseases, Respiratory Medicine, Dermatology and Anti-infectives & Vaccines.

Having key foci on Oncology and Rare & Orphan diseases means that we have expertise in developing and managing paediatric studies, often involving some of the most challenging indications.

…..BUT WITH WIDE EXPERIENCE
Vaccines: Prophylactic and Therapeutic
Cardiovascular Disease
Critical Care Medicine
Respiratory Medicine
Erectile Dysfunction
Muscular Dystrophy
Infectious Diseases
Gastroenterology
Paediatric Studies
Drug Addiction
Ophthalmology
Cystic Fibrosis
Rheumatology
Endocrinology
Haematology
Dermatology
Immunology
Anaesthesia
Neurology
Transplant
Psychiatry
Oncology
Analgesia
Urology
Asthma
COPD
AIDS

 

 

 

 

You can access the Oncology brochure here

 

 

 

 

You can access the Rare & Orphan brochure here

Oncology

Approximately 47% of Orion Clinical’s experience has been in oncology. We have delivered studies including > 5,200 patients in the last 5 years alone. As such, the majority of our staff have experience of working in oncology studies, many of which have also been considered rare/orphan conditions.Picture1

You can access the Oncology brochure here

 

Access Oncology case study here

Access Oncology case study here

Access Oncology case study here

Rare & Orphan

One of Simbec-Orion Group’s significant areas of expertise is the conduct of studies in Rare and Orphan indications. Over the last 19 years we have developed relationships with networks of specialist investigative sites and we have established and nurtured links with patient groups across Europe and North America.

We will develop elegant and effective solutions for your clinical development needs.

We can help you achieve faster approvals through our strategic development and Regulatory planning for Orphan indications

You can access the Rare & Orphan brochure here

 

 

Access Rare & Orphan case study here

Access Rare & Orphan WhitePaper here

WEBINAR Available Now Promo-Email Signature 001

 

Respiratory

At Simbec-Orion Group one of our core therapeutic areas is respiratory medicine. At our Simbec Research campus in Wales and in later phase clinical trials across Europe and North America we have delivered studies involving more than 3,500 subjects in over 40 studies.

To successfully deliver these studies we have developed relationships with networks of specialist investigative sites

These studies have provided us with extensive experience of conducting difficult clinical trials with inhaled drugs via a wide range of delivery systems:

  • Pressurised metered dose inhalers (MDIs)
  • Breath-activated inhalers MDIs and DPIs
  • Inhalers with spacer devices
  • Nebulisers including: Pari e-Flow & LC Plus

Picture2

 

 

 

 

 

 

 

 

 

Anti-Infectives & Vaccines

We have broad anti-infectives and vaccines clinical research experience and expertise; specifically we have recently been involved in many studies relating to both prophylactic and therapeutic vaccines.

Anti-Infectives-&-Vaccines-Pie-Chart---Infectious-Diseases-Studies

Dermatology

Simbec-Orion Group have significant experience in the development and delivery of dermatology clinical studies, both from our Research Campus in Wales and across a range of  tried and tested investigative sites in Europe and North America.

Therapeutic Experience over the last 5 years include:

  • Eczema
  • Herpes labialis
  • Psoriasis
  • Lupus erythematosous
  • Wound healing
  • Tinea versicolor
  • Genito-anal warts
  • Alopecia
  • Melanoma
  • Actinic Keratosis
  • Chronic plaque psoriasis
  • Acne rosacea
  • Eczematous dermatitis
  • Papulopustular rosacea
  • Hereditary palmoplantar kertodermas
  • Aesthetic enhancement, crow’s feet
  • PMLE
  • Ichthyosis

We have experience with a wide range of dermatology assessments/studies:

  • Cumulative irritation potential, Sensitization potential, Primary irritation potential
  • Proof of concept studies:
    • acne, atopic dermatitis, psoriasis
    • photoaging
    • wound healing
    • local anaesthetic, antipruritus
    • sampling techniques — skin biopsies, stripping, chemical and vacuum blisters
  • Phototoxicity, Photoallergy, Photosensitization (phototoxicity and photoallergy combined)
  • Simple patch
  • Repeated patch
  • Human repeat insult
  • Epilatory efficacy
  • Exfoliating effect
  • Firming properties
  • Moisturizing / Nourishing